Center for Clinical Pharmacology

Faculty at the Center

Alex Evers Headshot

Dr. Alex Evers, M.D.
Founder and Interim Director

Serving as interim director while also maintaining an active research lab at Washington University's Department of Anesthesiology.  Dr. Evers will lead the search for a permanent director in 2021.

Seibert headshot

Dr. Karen Seibert, Ph.D.
Founding Director

Expertise in clinical pharmacology and drug development, especially in the areas of pain and inflammation.

Burris headshot

Dr. Thomas Burris, Ph.D.
Alumni Endowed Professor and Vice President of Research

Expertise in targeting nuclear hormone receptors towards development of drugs to treat a range of human diseases including autoimmune diseases, cancer, metabolic/cardiovascular, and behavioral disorders.

Al-Hasani headshot

Dr. Ream Al-Hasani, Ph.D.
Assistant Professor

Studies ‭the negative affective behaviors associated with the withdrawal ‭phase of addiction and the interaction of endogenous opioid ‭systems with commonly prescribed opioid analgesics.

McCall headshot

Dr. Jordan McCall, Ph.D.
Assistant Professor

Expertise in neural mechanisms underlying the ‭emotional distress associated with stress, chronic pain, and ‭addiction.

Susruta Majumdar

Dr. Susruta Majumdar, Ph.D.
Associate Professor

Research is aimed at attaining functional selectivity of opioid agonist action from its own target adverse effects while integrating chemical synthesis with biochemical, genetic, and pharmacological approaches.

Che, Tao

Dr. Tao  Che, Ph.D.
Assistant Professor

Research in the Che lab is foucused on comprehensively characterizing and dissecting the molecular mechanisms of opioid receptor signaling in order to gain an atomic-level understanding of opioid receptor activation, and to use this information to develop chemical and synthetic biologic tools.

Kristine Griffett Headshot

Dr. Kristine Griffett, Ph.D.
Assistant Professor

Research is focused on identifying novel therapeutics for the treatment of metabolic diseases, including atherosclerosis obesity, diabetes, and non-alcoholic steatohepatitis (NASH).

Bahaa Headshot

Dr. Bahaa El-Gendy, Ph.D.
Assistant Professor

Research is concentrated on drug design and organic synthesis. He designs and synthesizes novel small organic molecules as modulators of nuclear hormone receptors for the therapeutic treatment of cancer, fatty liver diseases, Alzheimer’s Disease, and Atherosclerosis.

Cyrielle Headshot

Dr. Cyrielle Billon, Ph.D.
Assistant Professor

Researching novel nuclear receptor compounds to supress inflammasomes in myoblasts for the treatment of muscular dystrophy, in particular Duchene Muscular Dystrophy.

Lamees Headshot

Dr. Lamees Hegazy, Ph.D.
Assistant Professor

Computational scientist focusing on nuclear receptors structors and identification of novel ligands. 

Preparing the Next Generation of Professionals

In 2011, the National Institutes of Health identified a need to "recharge a dwindling cadre of experts in clinical pharmacology." By creating research opportunities, the Center will contribute to future health care needs by allowing students and researchers to expand their knowledge of clinical pharmacology research, implementation, and policy.

Recognizing that "Clinical Pharmacology" is inherently multidisciplinary, the Center for Clinical Pharmacology offers the opportunity for its students, post-graduates, and fellows to train in a collaborative environment that bridges basic biology, pharmacology, medicinal chemistry and clinical translation. Students and post-graduates are appointed at either the University of Health Sciences & Pharmacy or at Washington University School of Medicine, with full access to the academic resources at both institutions. 

Burris Lab Mtg

MAH Working Lab 1